Studies of alloantibody effect on skin graft survival in mice.

Alloantisera (anti-donor and anti-recipient alloantiserum) were prepared by skin grafting followed four inoculations of 1 x 107 splenocytes. These alloantisera were cytotoxic ( x 64) to target cells specifically. Anti-recipient alloantiserum was effective on enhancing skin graft survival in mice as same as anti-donor alloantiserum, when administered on the operative day, second postoperative day and fourth postoperative day between 50-200 μl at one time. (2) Lymphocyte cytotoxicity test 271